Directly LD-pumped passively Q-switched YVO<Subscript>4</Subscript>-Nd:YVO<Subscript>4</Subscript> laser at 1.34 μm with a V<Superscript>3+</Superscript>: YAG saturable absorber

The performance of a directly LD-pumped passively Q-switched YVO₄-Nd:YVO₄ laser at 1.34 μm with a V³⁺:YAG saturable absorber was demonstrated for the first time to the best of our knowledge. The average output power of 580 mW was obtained at the pump power of 8.8 W, corresponding to the optical conversion efficiency of 6.6% and slope efficiency of 11%. The minimum pulse width was 280 ns with the pulse repetition rate of 230 kHz, which was attained with a T = 5.6% output coupler at the pump power of 8.8 W.     

Nanoscratch study of Zn1−xMnxO heteroepitaxial layers

We investigated the nanotribological properties of Zn_1−xMn_xO epilayers (0 ≤ x ≤ 0.16) grown by molecular beam epitaxy (MBE) on sapphire substrates. The surface roughness and friction coefficient (μ) were analyzed by means of atomic force microscopy (AFM) and hysitron triboscope nanoindenter techniques.The nanoscratch system gave the μ value of the films ranging from 0.17 to 0.07 and the penetration depth value ranging 294-200 nm when the Mn content was increased from x = 0 to 0.16. The results strongly indicate that the scratch wear depth under constant load shows that higher Mn content leads to Zn_1−xMn_xO epilayers with higher shear resistance, which enhances the Mn-O bond. These findings reveal that the role of Mn content on the growth of Zn_1−xMn_xO epilayers can be identified by their nanotribological behavior.     

High Performance Thermally Activated Delayed Fluorescence Sensitized Organic Light‐Emitting Diodes

Recently, organic light‐emitting diodes (OLEDs) employing thermally activated delayed fluorescence (TADF) materials have aroused huge attention in both academia and industry. Compared with fluorescent and phosphorescent materials, TADF materials can theoretically capture 100 % excitons without incorporating noble metals, making them effective emitters and hosts for OLEDs simultaneously. Here, in this review, our recent works on mechanisms and materials of high performance TADF‐sensitized phosphorescent (TSP) OLEDs, TADF‐sensitized fluorescent (TSF) OLEDs and TADF‐sensitized TADF (TST) OLEDs are summarized. Finally, we propose the outlook for the further development and application of TADF‐sensitized OLEDs.     

Rapid determination of antiviral medication ribavirin in different feedstuffs using a novel magnetic molecularly imprinted polymer coupled with high‐performance liquid chromatography

A novel magnetic molecularly imprinted polymer adsorbing material was successfully synthesized to detect ribavirin in animal feedstuff. Molecularly imprinted polymer was prepared through surface polymerization by using ribavirin as template molecule, methyl methacrylate, and γ‐methacryloxypropyl trimethoxy silane functionalized magnetic mesoporous silica as bifunctional monomers, and ethylene diglycidyl ether as crosslinking agent. The prepared magnetic molecularly imprinted polymer was characterized by scanning electron microscopy and infrared spectroscopy. Static and dynamic adsorption experiments and selective adsorption analysis were performed to evaluate the adsorption and selectivity of magnetic molecularly imprinted polymer. Different experiments were conducted to optimize the magnetic solid‐phase extraction conditions. Under optimal experimental conditions, a magnetic molecularly imprinted solid‐phase extraction coupled with high‐performance liquid chromatography method was successfully developed for ribavirin detection. The established method achieved a satisfactory linear range of 0.20–50 mg/L (R² > 0.99) and a low detection limit (0.081 mg/kg). An average recovery of 92–105% with relative standard deviation of <6.5% was obtained upon the application of the developed method to detect ribavirin in real feedstuff samples. Thus, established method can be used for the rapid and simple separation and detection of added ribavirin in feedstuff.     

Liposomal Antitumor Vaccines Targeting Mucin 1 Elicit a Lipid‐Dependent Immunodominant Response

The tumor‐associated antigen mucin 1 (MUC1) has been pursued as an attractive target for cancer immunotherapy, but the poor immunogenicity of the endogenous antigen hinders the development of vaccines capable of inducing effective anti‐MUC1 immunodominant responses. Herein, we prepared synthetic anti‐MUC1 vaccines in which the hydrophilic MUC1 antigen was N‐terminally conjugated to one or two palmitoyl lipid chains (to form amphiphilic Pam‐MUC1 or Pam₂‐MUC1). These amphiphilic lipid‐tailed MUC1 antigens were self‐assembled into liposomes containing the NKT cell agonist αGalCer as an adjuvant. The lipid‐conjugated antigens reshaped the physical and morphological properties of liposomal vaccines. Promising results showed that the anti‐MUC1 IgG antibody titers induced by the Pam₂‐MUC1 vaccine were more than 30‐ and 190‐fold higher than those induced by the Pam‐MUC1 vaccine and the MUC1 vaccine without lipid tails, respectively. Similarly, vaccines with the TLR1/2 agonist Pam₃CSK₄ as an adjuvant also induced conjugated lipid‐dependent immunological responses. Moreover, vaccines with the αGalCer adjuvant induced significantly higher titers of IgG antibodies than vaccines with the Pam₃CSK₄ adjuvant. Therefore, the non‐covalent assembly of the amphiphilic lipo‐MUC1 antigen and the NKT cell agonist αGalCer as a glycolipid adjuvant represent a synthetically simple but immunologically effective approach for the development of anti‐MUC1 cancer vaccines.     

深度学习在超声检测缺陷识别中的应用与发展*

深度学习（Deep Learning）是目前最强大的机器学习算法之一,其中卷积神经网络（Convolutional Neural Network, CNN）模型具有自动学习特征的能力,在图像处理领域较其他深度学习模型有较大的性能优势。本文先简述了深度学习的发展史,然后综述了深度学习在超声检测缺陷识别中的应用与发展,从早期浅层神经网络到现在深度学习的应用现状,并借鉴医学影像识别和射线图像识别领域的方法,分析了卷积神经网络对超声图像缺陷识别的适用性。最后,探讨归纳了目前在超声检测图像识别中使用CNN存在的一些问题,及其主要应对策略的研究方向。     

电场条件下氧化锌结晶特性及极化产物的拉曼光谱分析

开展高压电场调控纳米材料结构形貌和性能研究在功能材料领域具有重要的理论和实际意义.本文在高压电场条件下合成了氧化锌纳米粉体,并对粉末试片进行了后期电场极化处理,研究了电场对氧化锌的结构形貌、点缺陷、拉曼光谱的影响.以X射线衍射仪(XRD)、扫描电镜(SEM)和拉曼光谱仪对产物的结构形貌、拉曼位移、缺陷分布等进行了表征.结果表明,高压电场条件下氧化锌的完全晶化时间和温度比未施加电场时明显延长和升高,直流电场能够显著促进前驱物中氧化锌的形核,并降低晶化速度.不同电场强度下氧化锌具有不同的显微形貌.纳米氧化锌粉末试片在直流电场中极化后,其阴极面和阳极面的拉曼光谱表现出明显的差异.有明显漏电电流的情况下,阳极面在1050 cm~(–1)处的二级光学声子模A_1(LO)的强度显著提高,且拉曼强度I_1=438 cm~(–1)和I_2=1050 cm~(–1)的比值与极化电场的场强呈线性关系.当调转试片正反面进行二次极化时,原来在阳极面尖锐的1050 cm~(–1)峰经过阴极极化而消失.阳极面1050 cm~(–1)拉曼峰的锐化与氧化锌晶粒内的缺陷重新分布和双肖脱基势垒有关.     

Multi‐Resonance Induced Thermally Activated Delayed Fluorophores for Narrowband Green OLEDs

High‐color‐purity emissions with small a full‐width at half‐maximum (FWHM) are an ongoing pursuit for high‐resolution displays. Though the flourishment of narrow‐band emissive materials with multi‐resonance induced thermally activated delayed fluorescence (MR‐TADF) in the blue region, such materials have not validated their potential in other color regions. By amplifying the influence of skeleton and peripheral units, a series of highly efficient green‐emitting MR‐TADF materials are firstly reported. Peripheral units with electron‐deficit properties can significantly narrow the energy gap for bathochromic emission without compromising the color fidelity. MR‐TADF emitters with photo‐luminance quantum yields of above 90 % with FWHMs of ≤25 nm are developed. The corresponding organic light‐emitting diodes show maximum external quantum efficiency/ power efficiency of 22.02 %/ 69.82 lm W^?1 with excellent long‐term stability.     

A bulk adjusted linear combination of atomic orbitals (BA-LCAO) approach for nanoparticles

We describe a bulk adjusted linear combination of atomic orbitals (BA-LCAO) approach for nanoparticles. In this method, we apply a many-body scaling function (in similar manner as in the environment-modified total energy based tight-binding method) to the DFT-derived diatomic AO interaction potentials (like in the conventional orbital-based density-functional tight binding approach) strictly according to atomic valences acquired naturally in a bulk structure. This modification, (a) facilitates all atom orbital-based electronic structure calculations of charge carrier dynamics in nanoscale structures with a molecular acceptor, and (b) allows to closely match high-level density functional calculation data (previously adjusted to the available experimental findings) for bulk structures. To advance practical application of the BA-LCAO approach we parameterize the Hamiltonian of wurtzite CdSe by fitting its band structure to a high-level DFT reference, corrected for experimentally measured band edges. Here, unlike in conventional DFTB approach, we: (1) use hydrogen-like AOs for the basis as exact atomic eigenfunctions, while orbital energies of which are taken from experimentally measured ionization potentials, and (2) parameterize the many-body scaling functions rather than the atomic wavefunctions. Development of this approach and parameters is guided by our goals to devise a method capable of simultaneously treating the problems of (i) interfacial electron/hole transfer between finite, variable size nanoparticles and electron scavenging molecules, and (ii) high-energy electronic transitions (Auger transitions) that mediate multi-exciton decay in quantum dots. Electronic structure results are described for CdSe quantum dots of various sizes. © 2018 Wiley Periodicals, Inc.     

Formation of liquid crystal/gel emulsions to nano-emulsions constructed by polyalkoxylated fatty alcohol (PAFA)-based mixed surfactant systems

In the construction of ternary phase diagrams, the polyalkoxylated fatty alcohol (PAFA)-based mixed surfactant systems including PAFA-AS (alkyl sulfonate), PAFA-CB (cocamidopropyl betaine) and PAFA-APG (alkyl polyglucosides) were used to develop self-standing liquid crystal/gel emulsions containing rapeseed oil methyl esters (ROME) and water. The formation of liquid crystal/gel emulsions are observed at semi-dilute regions of the phase diagrams. A pre-emulsion was chosen from each of PAFA-AS, PAFA-CB and PAFA-APG systems for minor modification with sodium silicate. Upon aqueous dilution of the modified pre-emulsions to weight fractions (Φ_w) of 0.8 and 0.6 and with an isothermal shaker agitation, the samples demonstrate dramatic increases in apparent viscosity with flow resistance and shear thinning behaviour. In oscillatory amplitude study, the emulsions show linear viscoelastic (LVE) plateau (G’>G”) and strain softening region (G”>G’) indicating the samples promote a viscoelastic behaviour. Further affirmation by Cole-Cole plots reveal the emulsion samples behave as a Maxwell fluid. The optical microscope study verifies the emulsions of PAFA-AS, PAFA-CB and PAFA-APG systems comprising of multilamellar vesicles, bicontinuous cubic phase and multilamellar phase, respectively. Upon aqueous dilution of the liquid crystal/gel emulsions with an isothermal agitation, the formation of nano-emulsion droplets is confirmed by transmission electron microscopy (TEM) and dynamic light scattering studies. The nano-emulsions display spherical and elliptical shapes with mean droplet sizes are in the range of 158.37 to 206.43?nm and zeta potential values are in the range of –12.07 to –32.79?mV.